CISA – Centro de Informação de Acidente de Trânsito e Álcool

Saiba o que o álcool faz no seu organismo e porque isso significa perigo ao volante. Acessar

Association between the Intron 8 VNTR Polymorphism of the DAT1 Gene and Crack Cocaine Addiction

This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users…

Effects of DRD2 splicing-regulatory polymorphism and DRD4 48 bp VNTR on crack cocaine addiction

There is evidence that dopamine receptors D2 (DRD2) and D4 (DRD4) polymorphisms may influence substance use disorders (SUD) susceptibility both individually and through their influence in the formation of DRD2–DRD4…

Effects of childhood trauma on BDNF and TBARS during crack-cocaine withdrawal

Objective To evaluate the association between childhood trauma (CT) and serum levels of brain-derived neurotrophic factor (BDNF) and thiobarbituric acid-reactive substances (TBARS) during crack-cocaine withdrawal. Acessar

The COVID-19 pandemic and its impact on substance use: Implications for prevention and treatment

The COVID-19 pandemic has brought major challenges to healthcare systems and public health policies globally, as it requires novel treatment and prevention strategies to adapt for the impact of the pandemic. Individuals with substance…

Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil

Suicide is a severe health problem, with high rates in individuals with addiction. Considering the lack of studies exploring suicide predictors in this population, we aimed to investigate factors associated…

Increased cortisol levels are associated with low treatment retention in crack cocaine users

Objective Our aim was to investigate the association between morning salivary cortisol levels and treatment retention in crack cocaine users. Acessar

Anger and substance abuse: a systematic review and meta-analysis

Objective Conduct a systematic review and meta-analysis to evaluate levels of anger among substance users compared to non-user controls and to analyze the possible association between anger and psychoactive substance…

Gender differences in progression to crack-cocaine use and the role of sexual and physical violence

OBJECTIVE: This study aimed to evaluate whether progression from first drug use to crack-cocaine use differs according to gender, and whether the report of sexual or physical violence impacts the time…

Assessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder

Objectives To evaluate the cognitive performance of individuals with alcohol (AUD) and/or crack cocaine use disorder (CUD) and polysubstance use using the MMSE and to investigate the impact of substance…