A systematic literature review on social determinations and consumption of psychoactive substances was realized. The research was accomplished in some databases, in Portuguese, English and Spanish, using the descriptors "Social…
To evaluate the association between contact, education and knowledge and the stigmatization of drug use/users among health professionals. This was a cross-sectional study with 449 professionals from health care services…
Cocaine-use disorder (CUD) has been associated with early life adversity and activated cellular immune responses. Women are most vulnerable to complications from chronic substance disorders, generally presenting an intense feeling…
Objective Cocaine is a highly addictive psychostimulant that affects synaptic activity with structural and functional adaptations of neurons. The transmembrane synaptic vesicle glycoprotein 2A (SV2A) of pre-synaptic vesicles is commonly…
The investigation of the effects of prenatal cocaine exposure (PCE) on offspring has been inconsistent, with few studies investigating biological outcomes in humans. We profiled genome-wide DNA methylation (DNAm) of…
Detoxification is frequently recommended as a treatment for moderate to severe Cocaine Use Disorder (CUD). However, the response to detoxification varies among patients, and previous studies have focused mostly on patterns of drug…
Reconhecida pela busca pelo bem-estar, a geração Z está consumindo menos bebidas alcoólicas em relação a gerações anteriores. Segundo a MindMiners, a partir do estudo “O Dossiê das Bebidas”, 45%…
Um estudo longitudinal conduzido na Dinamarca investigou a relação entre o consumo de álcool e o desempenho acadêmico de adolescentes. Utilizando dados do Estudo Nacional da Juventude Dinamarquesa, que incluiu…
This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users…
There is evidence that dopamine receptors D2 (DRD2) and D4 (DRD4) polymorphisms may influence substance use disorders (SUD) susceptibility both individually and through their influence in the formation of DRD2–DRD4…